Neuroendocrine predictors of dispersal behavior (Nikki Lee)

Hybrid: this project is scheduled to begin on 6/1/2026 and run for 6 weeks, finishing on 7/10/2026.

Project Description

For solitary rodents, dispersal marks a major geographic and social transition away from the close social environment of the family unit. This transition from social to solitary may be promoted by reduced social tolerance for family members, and/or by unrelated factors such as increased exploration and activity. Dispersal has impacts across multiple levels of biological organization, from population genetic diversity to individual fitness. Despite the prevalence and importance of dispersal in many species, the neural mechanisms underlying the timing and initiation of this process remain poorly understood. My lab aims to investigate what changes in the behavior of Belding’s ground squirrels, colonial tuco-tucos, Eastern gray squirrels, and fox squirrels during this transition—and what neuroendocrine mechanisms underlie this transition. Broadly, this research elucidates the neuroendocrine mechanisms underlying an important but understudied facet of mammalian biology by integrating laboratory neuroscience with study of behavior in naturalistic settings. Assessment of behavior in a laboratory setting allows for fine-grained analysis of the mechanisms underlying that behavior, while assessment of behavior in an animal’s complex natural environment allows a complete picture of the context in which that animal’s brain and behavior have evolved. However, few studies bridge the gap between lab-based studies of mechanism and field-based analyses of behavior. Students will be involved in tissue processing (e.g., slicing brains), literature searches, data analysis, behavioral scoring, and behavioral assays in the field.

Prerequisites

Students need to have already worked in my lab for one semester, or have already spoken to me about working in my lab in the future.

Special Comments

Project Information (subject to change)

Estimated Start Date: 6/1/2026

Estimated End Date: 7/10/2026

Estimated Project Duration: 6 weeks

Maximum Number of Students Sought: 3

Research Location: Hybrid

Travel Required? Yes (If “yes”: A subset of students will go to the field with me in July (our field site is outside of Yosemite National Park). )

Contact Information: Nikki Lee (email: nlee@wlu.edu)

Unraveling the Spider’s Internal Clock (Natalia Toporikova)

On campus: this project is scheduled to begin on 6/8/2026 and run for 8 weeks, finishing on 7/31/2026.

Project Description

Are you curious about how biological timekeeping systems develop? Join our research team investigating circadian rhythms in spiders across their development. You’ll maintain our spider colony, collect behavioral data using advanced locomotor monitoring systems, analyze patterns using Python,R and statistical methods, and conduct histological analysis to link molecular changes with behavior. This is a rare opportunity to work across the full research pipeline—from hands-on animal care to computational analysis—and contribute to fundamental questions about how nervous systems develop. No prior experience in all areas is needed; we’re looking for curious minds with genuine interest in biology, data science and willingness to think creatively.

Prerequisites

Interest in spiders

Special Comments

Project Information (subject to change)

Estimated Start Date: 6/8/2026

Estimated End Date: 7/31/2026

Estimated Project Duration: 8 weeks

Maximum Number of Students Sought: 2

Research Location: On campus

Travel Required? No (If “yes”: )

Contact Information: Natalia Toporikova (email: Toporikovan@wlu.edu)

CLOSED: Role of Uchl-1 during Optic Nerve Regeneration in Xenopus laevis (Fiona Watson)

On campus: this project is scheduled to begin on 6/08/2026 and run for 10 weeks, finishing on 8/14/2026.

Project Description

The Ubiquitin Carboxyl-Terminal Hydrolase L1 (uchl1) gene plays a role in protein degradation through the cell’s ubiquitin-proteasome system. Previous research in our lab demonstrated that Uchl1 protein expression is significantly upregulated in retinal ganglion cells (RGCs) during recovery from optic nerve injury. This project aims to localize Uchl1 expression in two distinct compartments: the RGC cell bodies in the retina and the RGC axons at the site of optic nerve injury. Using a uchl1 knockout frog model will enable us to investigate the functional role of uchl1 during optic nerve regeneration.

Prerequisites

animal training

Special Comments

Independent study during winter

Project Information (subject to change)

Estimated Start Date: 6/08/2026

Estimated End Date: 8/14/2026

Estimated Project Duration: 10 weeks

Maximum Number of Students Sought: 1

Research Location: On campus

Travel Required? No (If “yes”: )

Contact Information: Fiona Watson (email: watsonf@wlu.edu)

CLOSED: The Effects of Estrogen and Obesity on Rat Activity Patterns (Sarah Blythe)

On campus: this project is scheduled to begin on 6/01/2026 and run for 10 weeks, finishing on 8/7/2026.

Project Description

The Blythe lab is seeking 2–3 motivated undergraduate students to participate in an 8–10 week summer research (on campus) experience investigating how changes in estrogen, such as those occurring during menopause),influence behavior using a rat obesity model. Students will receive hands-on training in animal care, behavioral testing, and small rodent surgical techniques. Training will also include creating ethograms and analyzing behavioral data. Depending on project progress and student interest, opportunities may also include tissue sectioning, immunocytochemistry, and histological imaging and analysis. This experience is ideal for students interested in neuroscience, behavior, endocrinology, or biomedical research.

Prerequisites

Students selected for this position are required to enroll in Dr. Blythe‚Äôs Spring 2026 course – Behavioral Neuroendocrinology.

Special Comments

Yes, Behavioral Neuroendocrinology (Spring 2026).

Project Information (subject to change)

Estimated Start Date: 6/01/2026

Estimated End Date: 8/7/2026

Estimated Project Duration: 10 weeks

Maximum Number of Students Sought: 3

Research Location: On campus

Travel Required? No (If “yes”: )

Contact Information: Sarah Blythe (email: blythes@wlu.edu)

CLOSED: Scientific Writing in Neuroscience (Sarah Blythe)

Hybrid: this project is scheduled to begin on 6/08/2026 and run for 6 weeks, finishing on 7/17/2026.

Project Description

The Blythe lab is seeking 1 upper-level student to participate in a 4-6 week scientific writing internship.  This position can be either on- or off-campus.  The ideal research assistant will enjoy reading, writing, and revising scientific articles. Data analysis and figure design will also be required. Interested candidates are encouraged to contact Dr Blythe for more details. 

Prerequisites

Students should be rising juniors or rising seniors.

Special Comments

Project Information (subject to change)

Estimated Start Date: 6/08/2026

Estimated End Date: 7/17/2026

Estimated Project Duration: 6 weeks

Maximum Number of Students Sought: 1

Research Location: Hybrid

Travel Required? No (If “yes”: )

Contact Information: Sarah Blythe (email: blythes@wlu.edu)

CLOSED: Breathing as a Driving Force CLOSED: Behind the Fight or Flight Response to Stress (Ryan Brindle)

On campus: this project is scheduled to begin on 6/08/2026 and run for 10 weeks, finishing on 8/14/2026.

Project Description

When stressed breathing patterns change dramatically. However, the degree to which stress-related breathing drives the cardiovascular stress response (e.g., heart rate, blood pressure) is unknown. This project aims to document stress-related changes in breathing and cardiovascular activity and quantify the degree to which breathing drives cardiovascular changes under stress. Students working in the Sleep and Stress Laboratory will gain experience in human subjects research, learn the deep physiology of the fight or flight response, become proficient in measuring human respiratory and cardiovascular activity, and analyzing time series physiological data.

Prerequisites

None

Special Comments

None

Project Information (subject to change)

Estimated Start Date: 6/08/2026

Estimated End Date: 8/14/2026

Estimated Project Duration: 10 weeks

Maximum Number of Students Sought: 3

Research Location: On campus

Travel Required? No (If “yes”: )

Contact Information: Ryan Brindle (email: rbrindle@wlu.edu)